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AOD-9604

$99.99

AOD-9604 is a synthetic peptide fragment derived from the carboxyl (C-terminal) region of the human growth hormone molecule. It represents a 16-amino-acid segment corresponding to the lipolytic domain of growth hormone and has been explored extensively in scientific and preclinical research models. West Peptides supplies high-purity AOD-9604 in a lyophilized format.

All products are independently tested in certified U.S. laboratories to confirm identity, purity, and safety.
Our peptides are verified to exceed 99% purity for consistent and dependable research results

$99.99

AOD-9604 is a synthetic peptide fragment derived from the carboxyl (C-terminal) region of the human growth hormone molecule. It represents a 16-amino-acid segment corresponding to the lipolytic domain of growth hormone and has been explored extensively in scientific and preclinical research models. West Peptides supplies high-purity AOD-9604 in a lyophilized format.

Peace of Mind Guarantee

All products are independently tested in certified U.S. laboratories to confirm identity, purity, and safety.
Our peptides are verified to exceed 99% purity for consistent and dependable research results
Every order is processed and shipped within the United States to maintain quality and reliability.

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HCG

Defined Peptide Fragment for Laboratory Investigation

AOD-9604 is a synthetic peptide fragment derived from the carboxyl (C-terminal) region of the human growth hormone molecule. It represents a 16-amino-acid segment corresponding to the lipolytic domain of growth hormone and has been explored extensively in scientific and preclinical research models. West Peptides supplies high-purity AOD-9604 in a lyophilized format.

Scientific Background

AOD-9604 was originally developed during research efforts aimed at understanding how specific regions of the growth hormone molecule influence fat metabolism. The peptide represents the amino acid sequence 176-191 of growth hormone that was identified to have distinct metabolic effects in early laboratory studies.

Because of its specific structural design, AOD-9604 is referenced in scientific literature as a tool for investigating metabolic regulation, adipose tissue biology, and selective signaling pathways in controlled research environments.

Mechanisms Examined in Research

In preclinical models involving controlled experimental systems, AOD-9604 has been shown to engage with biological pathways related to fat mobilization and lipid metabolism:

  • Some research in animal models suggests AOD-9604 may enhance breakdown of stored lipids (lipolysis) and affect gene expression related to lipid handling.
    • Studies indicate this peptide fragment may increase fat oxidation and influence lipid regulatory pathways independently of canonical growth hormone signaling, possibly involving changes to receptor sensitivity.
    • Early investigations in rodent systems suggested potential effects on adipose tissue metabolism without the broader systemic effects associated with intact growth hormone.

These mechanisms are still subject to ongoing scientific study and remain topics of exploration in laboratory research.

Product Overview

AOD-9604 is supplied by West Peptides as a lyophilized (freeze-dried) peptide powder to support stability and ease of preparation. The format is intended to preserve structural integrity and facilitate dissolution with appropriate sterile solvents in laboratory workflows.

Researchers interested in metabolic regulation, lipid biology, and peptide signaling may incorporate AOD-9604 into experimental protocols that examine:

  • Peptide sequence engagement with cellular regulatory processes
    • Comparative analysis of metabolic pathways
    • Lipid mobilization and related signal transduction
    • Interactions between truncated peptide fragments and cellular receptors

This peptide fragment is suitable for use in controlled laboratory environments by qualified personnel.

Molecular Profile

Peptide Type: Synthetic peptide fragment
Sequence Basis: Human growth hormone C-terminal region (amino acids 176-191)
Form: White to off-white lyophilized powder
Purity: High analytical grade
Stability: Preserved under recommended laboratory storage conditions

West Peptides verifies each batch for composition and purity to support reproducibility in research applications.

Research Use Cases

AOD-9604 may be employed in research studies that involve:

  • Exploration of metabolic regulation pathways
    • Comparative peptide sequence analysis
    • Investigation of lipid handling and fat mobilization mechanisms
    • Structural analysis of peptide fragments in regulated systems

These applications reflect areas of scientific inquiry in which defined peptide fragments are used to probe molecular and cellular behavior.

Frequently Asked Questions (Research Context)

What is AOD-9604?
AOD-9604 is a synthetic peptide fragment derived from the carboxyl end of the human growth hormone molecule. It is referenced in scientific studies related to fat metabolism and peptide signaling.

Why is this peptide fragment studied in research?
Researchers use AOD-9604 to explore how a defined sequence from growth hormone influences selective metabolic pathways and lipid biology in controlled models.

How is AOD-9604 supplied for research use?
West Peptides supplies AOD-9604 as a lyophilized powder that can be dissolved with appropriate sterile solvents for laboratory preparation.

Can the mechanisms of AOD-9604 be generalized?
While some laboratory studies show engagement with lipid metabolism pathways in animal models, these findings are specific to controlled research settings and do not imply clinical effects.

Why do researchers choose fragments rather than full-length hormones?
Peptide fragments such as AOD-9604 allow scientists to isolate and study sequence-specific interactions and signaling outcomes in experimental systems without the complexity of full-length hormones.

Referenced Citations

Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 2001 Dec;142(12):5182-9. doi: 10.1210/endo.142.12.8522. PMID: 11713213.

 

Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D. Detection and in vitro metabolism of AOD9604. Drug Test Anal. 2015 Jan;7(1):31-8. doi: 10.1002/dta.1715. Epub 2014 Sep 10. PMID: 25208511.

 

Compliance Notice

This product is intended strictly for scientific research and controlled laboratory investigation. AOD-9604 is not approved by the United States Food and Drug Administration or any other regulatory authority for human or veterinary use. It is not intended for use as a drug, dietary supplement, cosmetic, or food product.

Our products are produced using a freeze-drying process (lyophilization), which helps maintain their integrity and stability during transit, typically for up to 3–4 months.

After the peptides are reconstituted (mixed with bacteriostatic water), they should be kept refrigerated to preserve their quality. Once in liquid form, they generally remain stable for up to 30 days when stored properly.

Lyophilization—also referred to as cryodesiccation—is a dehydration method where the material is first frozen and then exposed to low pressure. This allows moisture to transition directly from solid to vapor, leaving behind a dry, stable compound in the form of a light, crystalline powder. In this state, the product can be kept at room temperature until it is ready to be reconstituted.

Upon receiving your peptides, it is recommended to protect them from heat and light exposure. For short-term use (ranging from a few days to several weeks), refrigeration below 4°C (39°F) is suitable. Lyophilized products can also tolerate room temperature storage for a limited period if they will be used relatively soon.

For extended storage—spanning several months or longer—freezing is advised. Ideally, peptides should be kept at approximately -80°C (-112°F) to best maintain long-term stability

Research Use Only

All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease.
West Peptides is a chemical supplier. West Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. West Peptides not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.
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