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Melanotan-2

$99.99

Melanotan II (MTII) is a synthetic melanocortin peptide analog referenced in scientific and preclinical research involving receptor-mediated signaling pathways. With a well-characterized structure and affinity for multiple melanocortin receptor subtypes, Melanotan II is utilized as an investigational compound in controlled laboratory environments.

West Peptides provides high-purity Melanotan II in lyophilized form for use in analytical research and structured experimental applications.

All products are independently tested in certified U.S. laboratories to confirm identity, purity, and safety.
Our peptides are verified to exceed 99% purity for consistent and dependable research results

$99.99

Melanotan II (MTII) is a synthetic melanocortin peptide analog referenced in scientific and preclinical research involving receptor-mediated signaling pathways. With a well-characterized structure and affinity for multiple melanocortin receptor subtypes, Melanotan II is utilized as an investigational compound in controlled laboratory environments.

West Peptides provides high-purity Melanotan II in lyophilized form for use in analytical research and structured experimental applications.

Peace of Mind Guarantee

All products are independently tested in certified U.S. laboratories to confirm identity, purity, and safety.
Our peptides are verified to exceed 99% purity for consistent and dependable research results
Every order is processed and shipped within the United States to maintain quality and reliability.

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Melanotan II (MTII)

Melanotan II (MTII) is a synthetic peptide analog referenced in scientific and preclinical research involving receptor-mediated signaling pathways. Developed as a derivative of naturally occurring melanocortin peptides, MTII has been studied for its affinity toward multiple melanocortin receptor subtypes and its role in receptor-ligand interaction research.

West Peptides provides high-purity Melanotan II in lyophilized form for use in analytical research and structured experimental applications.

Product Overview

Melanotan II from West Peptides is supplied as a white lyophilized powder, formulated to support stability and precision in laboratory handling. The freeze-dried format allows for accurate reconstitution with sterile solvents and supports reproducibility in experimental workflows.

This synthetic peptide analog is frequently incorporated into research protocols examining melanocortin receptor activity, signaling pathways, and receptor-mediated biological processes in preclinical laboratory settings.

Research Background

Melanotan II belongs to a class of synthetic melanocortin analog peptides developed to interact with melanocortin receptor systems. These receptor systems are widely studied in molecular biology, biochemistry, and pharmacological research due to their involvement in cellular signaling and physiological regulation.

In controlled laboratory environments, Melanotan II is used to investigate receptor activation, signal transduction mechanisms, and peptide-receptor interactions. Its receptor-binding profile has made it a commonly referenced compound in studies involving melanocortin signaling pathways and molecular communication networks.

Due to its defined sequence and well-documented receptor affinity characteristics, Melanotan II is often utilized as a reference compound in experimental research involving receptor pharmacology and peptide-mediated signaling.

Molecular Profile

Peptide Type: Synthetic melanocortin analog peptide
Form: White lyophilized powder
Purity: High-grade analytical standard
Stability: Stable under recommended laboratory conditions

Each batch undergoes verification for purity and composition to ensure consistency in research applications.

Research Use Cases

Melanotan II is commonly used in laboratory research for applications such as:

• Preparation of peptide solutions for analytical or mechanistic assays
• Investigation of melanocortin receptor engagement and signaling pathways
• Comparative analysis in receptor-ligand interaction studies
• Development of in vitro models involving receptor-mediated biological processes
• Evaluation of peptide analog activity in controlled experimental systems

These applications reflect controlled research environments where defined peptide analogs are used to explore molecular signaling systems and receptor pharmacology.

Key Features

Defined Molecular Structure

Synthesized to correspond to a specific peptide sequence documented in scientific literature.

High Purity Verification

Batch-tested to support reproducibility and reliability in laboratory studies.

Lyophilized Format

Freeze-dried preparation helps maintain stability and enables controlled reconstitution.

Packaged for Research Environments

Supplied in secure vials suitable for handling in laboratory conditions.

Frequently Asked Questions

What is Melanotan II (MTII)?

Melanotan II is a synthetic melanocortin analog peptide studied for its interaction with melanocortin receptor systems in scientific and preclinical research.

Why do researchers use Melanotan II?

Researchers use Melanotan II in experimental models to investigate receptor-mediated signaling pathways, receptor activation mechanisms, and peptide-receptor interactions under controlled laboratory conditions.

What type of peptide classification does Melanotan II fall under?

Melanotan II is classified as a synthetic melanocortin analog peptide designed for receptor interaction and signaling studies.

Why is Melanotan II supplied in lyophilized form?

Lyophilization preserves peptide integrity during storage and transport, allowing researchers to reconstitute it under controlled laboratory conditions for consistent experimental use.

Referenced Citations

Hruby VJ, Lu D, Sharma SD, Castrucci AL, Kesterson RA, Al-Obeidi FA, Hadley ME, Cone RD. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5,D-Phe7,Lys10] alpha-MSH(4–10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity. J Med Chem. 1995;38(18):3454–3461.

Hadley ME, Dorr RT. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006 Apr;27(4):921–930. doi:10.1016/j.peptides.2005.01.022.

Wikberg JE, Muceniece R, Mandrika I, Prusis P, Lindblom J, Post C, Skottner A. New aspects on the melanocortins and their receptors. Pharmacol Res. 2000 May;42(5):393–420. doi:10.1006/phrs.2000.0706.

Compliance Notice

This product is intended strictly for laboratory research and scientific investigation purposes only. Melanotan II (MTII) is not approved by the United States Food and Drug Administration or any other regulatory authority for human or veterinary use. It is not intended for use as a drug, dietary supplement, cosmetic, or food product.

Our products are produced using a freeze-drying process (lyophilization), which helps maintain their integrity and stability during transit, typically for up to 3–4 months.

After the peptides are reconstituted (mixed with bacteriostatic water), they should be kept refrigerated to preserve their quality. Once in liquid form, they generally remain stable for up to 30 days when stored properly.

Lyophilization—also referred to as cryodesiccation—is a dehydration method where the material is first frozen and then exposed to low pressure. This allows moisture to transition directly from solid to vapor, leaving behind a dry, stable compound in the form of a light, crystalline powder. In this state, the product can be kept at room temperature until it is ready to be reconstituted.

Upon receiving your peptides, it is recommended to protect them from heat and light exposure. For short-term use (ranging from a few days to several weeks), refrigeration below 4°C (39°F) is suitable. Lyophilized products can also tolerate room temperature storage for a limited period if they will be used relatively soon.

For extended storage—spanning several months or longer—freezing is advised. Ideally, peptides should be kept at approximately -80°C (-112°F) to best maintain long-term stability

From Synthesis to Delivery

The Peptide Manufacturing
Process — 9 Steps

A precision-driven journey from pharma-grade raw materials to your doorstep, ensuring the highest purity, stability, and quality at every stage.

01 Phase 1 — Synthesis
Step 01
Pharma-Grade Raw Materials
Every peptide begins with high-purity, pharma-grade amino acid building blocks sourced from trusted suppliers. Using premium raw materials ensures the synthesis process starts with the highest possible quality foundation.
01
Step 02
Precision Peptide Chain Assembly (SPPS)
Peptides are constructed using Solid Phase Peptide Synthesis (SPPS), where amino acids are sequentially added to a resin-bound chain. This controlled process allows precise formation of the peptide sequence with high accuracy.
02
Step 03
Controlled Resin Cleavage
Once synthesis is complete, the finished peptide chain is carefully separated from the solid resin support. This controlled cleavage step releases the peptide while preserving structural integrity.
03
Step 04
Primary Peptide Recovery
The crude peptide is isolated from the reaction mixture and collected. This stage removes bulk reaction solvents and prepares the material for advanced purification.
04
02 Phase 2 — Purification & Testing
Step 05
Advanced HPLC Purification
High-Performance Liquid Chromatography (HPLC) is used to separate the target peptide from impurities and incomplete fragments. This purification step ensures high peptide purity and consistency.
05
Step 06
Analytical Identity & Purity Verification
Each batch undergoes analytical testing such as HPLC and mass spectrometry to confirm molecular identity and verify purity levels before proceeding to the final stages.
06
03 Phase 3 — Stability & Delivery
Step 07
Stability-Preserving Lyophilization
The purified peptide solution is freeze-dried (lyophilized) into a stable powder form. This process improves shelf life, preserves molecular structure, and allows long-term storage.
07
Step 08
Sterile Vialing & Medical-Grade Storage
Peptides are filled into sterile laboratory vials and stored under controlled low-temperature conditions to maintain stability, purity, and product integrity.
08
Step 09
Express US Shipping (2–3 Days)
Orders are securely packaged and shipped through trusted domestic carriers, ensuring fast and reliable delivery across the United States within 2–3 business days.
09

Research Use Only

All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease.
West Peptides is a chemical supplier. West Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. West Peptides not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.
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